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Results We demonstrate a developmental perturbation in CCK-expressing excitatory neurons within the mPFC: their density increases sharply in early postnatal life, stabilizes during adolescence, and typically declines in adulthood in wild-type (WT) mice, yet remains persistently elevated in adult KI counterparts

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Non-CYP Phase I and Phase II enzyme profiles mirrored these trends, peaking between Days 15 and 30 (Fig