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However, the failure of many antioxidant clinical studies suggests that a sound mechanistic approach is ultimately needed to improve the design of future studies

That is, low GSH could be due to low production of GSH OR it could be due to high production but also high reducing activity due to a high oxidative load (reflected in high levels of GSSG)

Experimental evidence supports the theoretical understanding that as the polyene chain length of carotenoids increases, i.e., the conjugated -electron system becomes more extended, the HOMO level of carotenoids decreases, and their 1 O 2 quenching activity becomes stronger

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Contribution of adipogenesis to healthy adipose tissue expansion in obesity

Taylor J