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Recently, the new molecular details of WD progression and metabolic signatures of WD phenotypes began to emerge

demonstrated that macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques (65)

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Within mitochondria, copper ions catalyze the oxidation of NADH molecules by hydrogen peroxide, resulting in the production of NAD + ions

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Brimonidine is felt to have a dual mechanism of action by reducing aqueous humor production and increasing uveoscleral outflow