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To test this, we looked for regions of LOH where high predicted neo-antigenicity and high rates of non-synonymous mutations were mutually exclusive, finding no such inverse association in 7 of 8 patients tested (Supplementary Table 9), although several patients could not be tested due to low numbers of mutations

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Development 148 , dev199381 (2021)

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Measurement of Carnitine, TMAO, -butyrobetaine, d9-carnitine, d9-TMAO, and d9--butyrobetaine Sample preparation and quantification for carnitine and TMAO in healthy volunteers Fifty microliters of plasma and 50 L urine samples were extracted with 450 L and 950 L methanol containing 200 ng/mL isotopically labeled internal standards (d3-carnitine and d9-TMAO) respectively, and the extraction was performed using the Geno/Grinder 2010 (SPEX SamplePrep., Metuchen, NJ, USA) at 1000 rpm for 3 min

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Pair It With Carbs (Yes, Really) : This surprises some people, but insulin helps drive L-Carnitine into muscle cells

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doi: 10.1080/00365510701810613

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