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Setmelanotide also demonstrated positive results in metabolic studies in DIO NHPs

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[20] A mutation in the human TRP-1 gene may result in the deregulation of melanocyte tyrosinase enzymes, a change that is hypothesized to promote brown versus black melanin synthesis, resulting in a third oculocutaneous albinism (OCA) genotype, "OCA3"

Each one includes reference dose ranges, dosing frequency, and half-life for every peptide it covers

Epidemiological studies reported an association between HDP and ASD
