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Previously, the patient was seen at his oncology clinic for evidence of cancer progression on his current chemotherapy, rituximab and polatuzumab vedotin, due to an increase in the growth of a bulky tumor on the patients back ( Figure 2 ) The patient was urgently started on a new chemotherapy regimen consisting of ifosfamide, carboplatin and etoposide
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On the one hand there is data suggesting that arginine deprivation is correlated with a delay in the development of some tumor cells (166)

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