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Recent studies have shown that C16-carnitine induces mitochondrial dysfunction and leads to calcium overload by increasing mitochondrial fission in SH-SY5Y cells

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Treatment with multi-strain probiotic VSL#3 did not appear to reduce the elevated TMAO level in plasma caused by a high-fat diet ( Streptococcus thermophilus , Lactobacillus acidophilus , and Bifidobacterium longum ) for 3 months, there was no change in TMAO level, but the betaine level in plasma was significantly increased (Table 1) ( TABLE 1 Probiotic/prebiotic that effect TMAO level

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