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5-Amino-1MQ binds the NNMT active site with high selectivity and is widely used in published research as a chemical probe for NNMT function
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The absence of severe thrombocytopenia and the presence of macrocytosis and highly elevated LDH suggested PTMA due to vitamin B12 deficiency

Current human studies show that AOD9604 is safe and well-tolerated, but there is no strong evidence that it effectively promotes fat loss in humans

Its not clear why this occurs, but some doctors have reported cases of fever that has normalized after treatment with low levels of vitamin B12
