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As discussed, the bioavailability of cortisol at the site of inflammation is an active, enzymemediated event

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doi: 10.1007/s11064-013-1017-0 43 PetersD.BengtssonB.HeijlA

As regards the biological function, a significant proportion of them is involved in the generation of precursor metabolites and energy, including glucose metabolism, and oxidative phosphorylation [38]

Conclusions The combined effects of exercise and polyphenol supplementation offer a promising, non-pharmacological approach for managing depression and enhancing brain function