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A deficiency can also cause a condition called megaloblastic anemia which creates larger, immature, and abnormal red blood cells and leads to impaired DNA synthesis

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This regulatory situation creates challenges

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Others who may be more susceptible to vitamin B12 deficiency are patients diagnosed with Crohns disease or celiac disease, and those who have undergone intestinal procedures such as weight loss surgery

These findings indicated that BDNF signaling is deregulated in AD, leading to cognitive impairment and memory loss (Fig