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Various physiological & pathological states, such as wound healing or regeneration after damage can be connected with these processes

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Registered Clinical Trials on Potential Therapeutic Targets and Agents in AUD-Related Oxidative Stress Most of the registered clinical trials investigated the effect of N-acetylcysteine (NAC) on AUD

[DOI] [PMC free article] [PubMed] [Google Scholar] [383].Eljaja L, Bjerrum OJ, Honor PH, Abrahamsen B, Effects of the excitatory amino acid transporter subtype 2 (EAAT-2) inducer ceftriaxone on different pain modalities in rat, Scand J Pain 2(3) (2018) 132136

It reduces the expression of chemokines MCP-1 and RANTES, which are essential for TAM recruitment, and further suppresses TAM activation by decreasing M2 macrophage markers and tumor-promoting factors like MMP-2, MMP-9, and VEGF