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Description
The penetrance for melanoma in kindreds with CDKN2A mutations is estimated at 58% to 92% by 80 years of age and varies with geography
The etiology of IBD is multifactorial, involving complex interactions among genetic predisposition, environmental factors, the intestinal microbiome, and the immune system (1316)

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Riccardi VM, Powell PP

doi: 10.3390/neurolint15020045
