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The review concludes that combining different approaches is the most effective way to treat hyperpigmentation

McKusick V, Phillips JI

It can cause joint damage, malformation, incapacity, swelling, and pain in numerous joints (Sharif et al., 2018)

moderate impairment, n = 7

This is the first RCT of repeated ketamine dosing in patients with TRD, in which two- and three-times weekly treatment schedules over up to 4 weeks showed comparable efficacy that was superior to placebo

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