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Consistent with the human genetic study, PGRN deficiency has been shown to exacerbate Gaucher disease-associated phenotypes of Gba1 D409V/D409V knockin mice [214]
[PubMed] [Google Scholar] 591
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Nucci C, Tartaglione R, Cerulli A, Mancino R, Span A, Cavaliere F, Rombol L, Bagetta G, Corasaniti MT, Morrone LA
doi: 10.1038/onc.2015.282
