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256,257 Oral vitamin C can promote diabetic foot ulcer wound healing by enhancing the reducing oxidative stress

However, limitations include in vivo instability, reliance on biocompatible and robust carriers and restricted application procedures (local and direct)

PMID 34046142

doi:10.1016/s0009-9120(00)00199-5 Sun Y, Sun M, Liu B, et al

By its upstream action of inhibiting lipid peroxidation, GPX4 can indirectly but effectively reduce the expression levels of these destructive enzymes, thereby delaying or preventing ECM breakdown (Xiao et al., 2024) (Figure 1)

[DOI] [PubMed] [Google Scholar] 14.Kesari K.K., Agarwal A., Henkel R
