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Conversely, and interestingly, UGTs present in the bladder can protect against accumulation of toxins since they are highly expressed on the surface of bladder tissue, particularly in females where it is postulated that the lower incidence of bladder cancer is related to increased UGT isoform activity

doi: 10.1097/00000542-200312000-00027

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EASL clinical practice guideline: occupational liver diseases

Some researchers have developed supramolecular nanoparticles that combine the phosphodiesterase 4 (PDE4) inhibitor crisaborole and the ferroptosis inhibitor DFO