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This suggests that it may be most effective in combination with other agents

On the other hand, cancer cells sometimes exploit a reversible inactivation of GAPDH via oxidative modification of its active-site cysteine (a GAPDH redox switch), which diverts glucose flux into the pentose phosphate pathway to generate NADPH for antioxidant defense 114

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2004;59:M178M183

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The effect of SF on the gut microbiome may also affect the production of short-chain fatty acids (SCFA) like butyrate, which have neuroprotective effects [149,150]