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Quick-Weller J
doi: 10.1016/j.ejphar.2013.10.002
By combating oxidative stress, glutathione supports the bodys natural detoxification processes and helps maintain cellular integrity
This observation is not surprising considering the loss of function of pVHL in a number of renal cancers leading to stabilization of HIF- and subsequent pseudohypoxic possibly resulting in an increased activity of GCLC and GCLM
Indeed, exploratory analysis of SZ and OD subgroups in the present study reveal mixed outcomes in relation to BOLD-fMRI, albeit impacting healthy control outcomes as well as patients, therefore more likely attributable to differing levels of variability between the subsamples, rather than a clear difference in function between the diagnostic groups in this instance
Uncontrolled nuclear localization of MiT/TFE transcription factors increases the basal presence of lysosomes
