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When combined with liver malignancies, cirrhosis accounts for 3.5% of all deaths worldwide (Asrani et al., 2019)

Pathol Res Pr

Archives of Virology, Volume 170, article number 1

The HPV16 E7 oncoprotein directly suppresses the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) signaling pathway, significantly reducing the expression of genes that encode type I interferon and pro-inflammatory proteins, hence facilitating immune evasion in several HPV-related tumors in murine models (Luo et al., 2020)

[DOI] [PMC free article] [PubMed] [Google Scholar] 96.Jairath V., Feagan B.G
