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However, no clinical trials have been reported that provide any evidence of its effectiveness for raising the chronically low homeostatic level of glutathione that occurs in primary mitochondrial diseases [1, 11]

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Asian Pac J

In one study [76] taking 4000 mg of omega-3 supplements daily for 12 weeks led to a better GSHcreatine ratio and reduced depressive symptoms in older adults who had a higher risk of developing depression compared with the control group taking a placebo

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