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doi: 10.3389/fimmu.2025.1703672 Received 12 September 2025 Accepted 17 October 2025 Published 31 October 2025 Volume 16 - 2025 Edited by Kosuke Nishi, Ehime University, Japan Reviewed by Abdullah Shaito, Qatar University, Qatar Rezvan Yazdian-Robati, Mazandaran University of Medical Sciences, Iran Updates Copyright 2025 Liu and Jiao