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IVP is a holder of the worldwide patent (including PCT International Publication Number WO 2004/028536 A1) for the application of N -acetylcarnosine for the treatment of ophthalmic disorders, including cataracts

However, it has been shown that vitamin B3 supplementation in the form of niacin helps to restore cellular NADH/NAD + balance and encourages mitochondrial biogenesis in human fibroblasts from a complex I disease patient[29], and has been shown to improve survival in a respiratory chain complex I disease C

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