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Endoscopy 2003;35:4115

In contrast to the findings of the present and previous studies [19,20], other results found an increase of MDA and a decrease of GSH levels in human HCC tissue compared to healthy or benign liver tissue [1,11,25,31]

The human body uses oxygen as the primary oxidant in energy producing biological reactions, yet this aerobic mechanism is associated with the generation of highly reactive and potentially harmful (free radical) molecules

- Contribui para o estimulo da produo de colgeno, contribuindo para maior elasticidade

The promotor of the gene driving expression of the Gpx4 gene for example is less methylated in cancer cells contributing to higher levels of the protein in these cells [290], whereas elevated methylation of GpG islands of Gpx4 and FSP1 leads to diminished protein levels [291]

The most striking effects were observed with VLDL: addition of this type of lipoprotein strongly reduced the induction of STAT3 phosphorylation by CLCF1