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Since Fe 2+ in the labile iron pool is the specific substrate for ferroptosis, and rises with aging in C

"It occurs in people whose B12 deficiency is caused by pernicious anemia," explains vitamin B12 expert and researcher Ralph Green, MD, PhD, a Distinguished Professor at the UC Davis School of Medicine

Microbiology 143 , 18851889 (1997)

Given that pharmacological inhibition of cystine uptake induced ferroptosis 19 , we explored whether ferroptosis is induced by cystine- and GSH-depletion

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