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Description
Animals were trained for 3 consecutive days prior to MCAO, with three trials per day
Extended phase: weeks four through eight By weeks four through eight, substantial healing progress is often evident for responding individuals
Subsequently, after local anesthesia is applied, the PRP is injected into the injured tissue
Please note that the FDA and EMA first-in-human guidance applies to multiple phases of first in human trials and not only to Phase 0
However, clinical trials in humans have demonstrated mixed results
Its good for patients with severe deficiencies or who need quick treatment
