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Haddy FJ, Scott JB: Metabolic factors in peripheral circulatory regulation

This is important for rosacea, because symptoms such as redness are less noticeable in darker skin and treatments such as laser, medication or creams can have a greater risk of pigment changes

Reconstitution requires an 18-20 gauge draw needle to transfer bacteriostatic water without creating rubber stopper particulate, while injection requires a 29-31 gauge insulin syringe for subcutaneous administration

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