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However, small modifications to both the amino group and the methoxy group at position 5 of the benzothiazole core did not result in any significant increase or decrease in binding activity as measured by the CPMG assay, and no reliable LO-NMR K D data could be obtained for the analogues (Supplementary Table 1)

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PZA and INH treatment to in vitro granulomas generated from T2DM subjects at 3-months post- L-GSH supplementation also resulted in a significant decrease in the production of IL-6 when compared to before L-GSH supplementation in the untreated (control) category ( Figure 7A )

By integrating clinical and molecular data, including serum metabolite levels, the artificial neural network (ANN) was trained to identify patterns associated with different WD phenotypes, which differ in hepatic, neurological, and asymptomatic manifestations

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