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& Bulleid, N.J

Conclusion and outlook Autophagy is a degradation process controlled by a cascade of ATG protein complexes, each of which regulates different stages of initiation and formation of autophagic membrane structures

This results in 8-oxoG pairing with cytosine (C) in trans and adenine (A) in cis during DNA replication, potentially leading to base pair mutations and impairing DNAs normal function, as depicted in Figure 1

Hu, D., Xie, Z., Ye, Y., Bahijri, S., & Chen, M

Take a holistic route

*Correspondence: Maohua Zheng, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers