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Existing studies indicate that in the central nervous system, copper can drive protein misfolding and aggregation to exacerbate neuronal injury, but it can also participate in the activation of antioxidant enzymes and repair factors to inhibit excessive cell death and inflammation, demonstrating a double-edged sword effect

Manipulation of GCK expression within the ARC of experimental animals alters glucose intake

An emerging strategy in neural tissue engineering involves the development and application of so-called living scaffolds, which are defined as constructs with a preformed, often anisotropic architecture, consisting of living neural cells within a 3-D biomaterial matrix

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doi: 10.1186/s12883-021-02257-x, 43

Many dermatologists recommend punch excision or grafting for severe ice pick scars, with copper peptides potentially playing a supporting role in healing