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Primary carnitine deficiency (PCD) is an autosomal recessive disorder characterized by a lack of plasma membrane carnitine transport owing to a shortcoming in the OCTN2 carnitine transporter

After induction of hypertone, a strong positivity to Ub is detected (lane 3), which is significantly reduced in the retina concomitantly treated with carnitine (lane 2)

Therefore, mitochondria-associated synaptic abnormalities are likely to contain robust therapeutic targets for ASD that have yet to be discovered

However, there isnt an established Recommended Dietary Allowance (RDA) for L-carnitine, as the body is typically able to produce enough L-carnitine if there is enough protein in the diet

doi:10.1016/j.rbp.2013.01.004