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J Biol Chem 273: 3371433721 [DOI] [PubMed] [Google Scholar] Rahimi N., Tremblay E., McAdam L., Park M., Schwall R., Elliott B

[PMC free article: PMC3272390] [PubMed: 19622820] 491

Interestingly, relatively little change was seen in the prefrontal cortex of patients, an observation that was also confirmed in a later direct MRS study (133)

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The transcription factor Forkhead box O3a (FOXO3a) also regulates multiple antioxidant genes and is reduced in COPD lungs as a result of phosphoinositide-3-kinase (PI3K) activation [18,50]

Essential Cofactors: Selenium and Vitamin C To function properly, the systems in your body that manage antioxidants require "helpers" called cofactors