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Acta 930 , 173178 (1987)

The anti-inflammatory effects were equally notable, with lower interleukin-1 and tumour necrosis factor-alpha levels, highlighting curcumins ability to disrupt the cycle of inflammation that fuels both insulin resistance and hepatic damage

Endothelial cells Endothelial cells are a core component of the BBB, but endothelial cells in the BBB do not have the same structure and function as endothelial cells in other parts of the body[16]

Further, a placebo-controlled trial in 152 elderly adults (aged 70-80 years) with mild cognitive impairment reported that B vitamin supplementation (50 mg/day of vitamin B 6 , 5 mg/day of folic acid, and 0.4 mg/day of vitamin B 12 ) for one year did not improve performance on a similar test of verbal fluency (136)

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Mutant forms of SOD appear to lead to mitochondrial dysfunction (Liu 2004)