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This approach yielded an effective peptide based on S 71 82 with N-methylated C-terminal Val (VAQKTmV), corresponding to residues 7182 which were found to constitute a self-recognition element within native S [52]

As stated in their report, the deciency in vitamin B12 hinders the methionine generation, which is relevant to the synthesis of myelin and neurotransmitters

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