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Third, iron can have numerous effects beyond inducing ferroptosis, such that the accumulation of iron is not synonymous with ferroptosis

Nanoparticle-based artificial RNA silencing machinery for antiviral therapy
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The differential metabolite N-acetylglutamate (NAG) activates the KEAP1-NRF2 pathway and concurrently inhibits ferroptosis, thereby mediating a protective effect
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Collectively, HDL has multiple biological mechanisms that inhibit thrombus formation, and thus, contribute to HDLs anti-atherogenic properties