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Description
Nat Immunol (2015) 16(4):34353.10.1038/ni.3123 11 PachecoARBarileDUnderwoodMAMillsDA

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Tolerance A state of immune unresponsiveness to an antigen that results from the suppression of immune responses to antigens that have been administered or encountered previously

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In general, yes for several structural reasons
Nat Med 2020;26:3205
