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Particular focus should be placed on interactions between mHTT, the ironmetabolism axis (such as transferrin receptor 1 and hepcidin), and key ferroptosis mediators (GPX4 and Nrf2) to build a dynamic model linking mHTT aggregation, iron dysregulation, and neuronal ferroptosis, and to define subtype-specific vulnerability of MSNs

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10.1039/c5bm00161g 22 CaoY.da Silva AraujoM.LorangC

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36 Some of the enzymes whose interactions with melatonin have been studied include glutathione reductase (GRd), GPx), and glucose-6-phosphate dehydrogenase

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Randomised trial of chronic supplementation with a nutraceutical mixture in subjects with non-alcoholic fatty liver disease

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Yes, and recurrence is common when only the bacteria are treated without addressing the root cause

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