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In vitro and in vivo Down syndrome models revealed that supplementation of mice with low molecular weight antioxidants such as -tocopherol reduced the level of oxidative stress, attenuated degeneration of cholinergic neurons, and improved working memory (Lockrow et al

Weeks 13-16: 10mg (1.0mL or 100 units)

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The study design was guided by pilot studies and feedback from local PCPs 2,42

Model assumptions were assessed by residual analysis

The levels of protein-bound glutathione in patients in the current study were considerably higher than those of healthy volunteers in previous studies [12] estimated using the same method