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All experiments were carried out in accordance with the Guide for the Care and Use of Laboratory Animals [20] and with approval from the Institutional Animal Care and Use Committee at the University of Texas Medical Branch

Individual variation in NNMT expression NNMT expression varies significantly between individuals

Adults over 60 still technically need around 2.4 mcg daily, but absorption becomes weaker with age

Office of Dietary Supplements Vitamin B6. NIH Office of Dietary Supplements, U.S

Vitamin B12 is essential for red blood cell formation, neurological function, and DNA synthesis

Disease activity is classified as: Remission: No active symptoms