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185 Pyruvate kinase deficiency has a protective effect against replication of the malarial parasite in human erythrocytes.13,58 This protective effect may be related to reduced ATP levels in PK-deficient red blood cells

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Sialic acid-siglec axis in human immune regulation, involvement in autoimmunity and cancer and potential therapeutic treatments

Data from several controlled and uncontrolled studies of adjunctive oral NAC 1 g twice daily have shown beneficial effects on the depressive component of bipolar disorder during maintenance phase treatment [142, 152-157]

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