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Another study found that topical application of glutathione reduced the appearance of acne scars and hyperpigmentation

Zhang LQ, Che CX, Du YQ, Han LL, Wang JL, Zhang CY

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While many of the key regulators of this pathway remain largely unknown, recent studies have identified glutathione peroxidases, particularly glutathione peroxidase 4 (GPX4), as antioxidant enzymes that can prevent lipid peroxidation using reduced glutathione (GSH) as a co-factor 9,10

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Therefore, both in vivo and in vitro experiments indicate that AMPK can play a role in protecting against oxidative damage, possibly by inhibiting ferroptosis to provide neuroprotection (97)