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Description
The pathways that appear active in those models do not automatically translate to predictable, beneficial effects in human patients
Arshi, A., Nakashima, Y., Nakano, H., Eaimkhong, S
Mauras N, Haymond MW
found that the lncRNA CRNDE triggers protective autophagy by upregulating ATG4B in HCC cells via sequestration of miR-543, whereas sorafenib therapy activates the CRNDE/ATG4B/autophagy pathway and reduces sorafenib sensitivity in HCC [86]
Nalle SC, Turner JR
Ketone bodies and two-compartment tumor metabolism: stromal ketone production fuels mitochondrial biogenesis in epithelial cancer cells
