glutathione peroxidase hepatic A novel upregulation of 1 by knockout of liver-regenerating protein Reg3β aggravates acetaminophen-induced protein nitration Effect of knockout of glutathione

This work is the result of NIH funding, in whole or in part, and is subject to the NIH Public Access Policy

2013;8:e58798

It captures lipid peroxides through its lipophilic properties, downregulating prostaglandin-endoperoxide synthase 2 (PTGS2), upregulating GPX4, and nuclear factor erythroid 2-like 2 (NFE2L2) ( 2.5 Liproxstatin-1(Lip-1) Lip-1 is a specific inhibitor of LPO, and its mechanism of action in clearing LPO is similar to that of Fer-1

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