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Abstract Ferroptosis is a recently recognized form of non-apoptotic regulated cell death and usually driven by iron-dependent lipid peroxidation and has arisen to play a significant role in cancer biology

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Analyses of increased PI3K activity (either via a gain-of-function mutation or elimination of PTEN from B cells) as well as selective chemical inhibition of the p110 catalytic isoform have shown that overall, PI3K tends to inhibit Ig class switching [129,130,131,132]

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