gene glutathione peroxidase 3 Glutathione Peroxidase 3 (GPX3) Human

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Continuous administration of any bioactive compound can lead to downregulation of its target receptors, diminishing its effects over time

We know that macrocytosis is a very, very late stage of B12 deficiency and that severely deficient patients may not present with this sign, the administration of folic acid also masks macrocytosis by normalising the size of the blood cells

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doi: 10.1016/j.ejca.2006.05.037

Thus, we hypothesized that a molecule specifically expressed on the endometrial surface could be targeted by a peritoneally injected drug if that marker is not expressed by other peritoneal surfaces