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February 29, 2024

Remedial efficacy of a new cationic liposome-nano-formulated all-trans-retinoic acid (0.60 mg/kg/day for 30 days) in the mice model of lung cancer revealed that the formulation of lipo-all-trans-retinoic acid in 1, 2-dioleoyl-3-trimethylammonium-propane (DOTAP) and cholesterol in the ratio of 70:20 was the suitable carrier for ATRA in treating lung cancer (Grace and Viswanathan, 2017)

Crit Care 17:R294 Mekontso-Dessap A, Castelain V, Anguel N, Bahloul M, Schauvliege F, Richard C, Teboul JL (2002) Combination of venoarterial PCO2 difference with arteriovenous O2 content difference to detect anaerobic metabolism in patients

Xayarath and Freitag, 2012)

Artificial intelligence (AI) and computational modelling are also expected to play a central role by enabling predictive simulation of airflow, particle trajectories, and regional deposition, as well as optimisation of formulation-device combinations and personalised dosing strategies

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