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In IBS-C patients, acute mental and acoustic stress slow intestinal motility and increase the colonic spike-burst activity with higher levels of the vital stress hormone corticotropin-releasing factor (CRF)
"GlyNAC supplementation in old mice improves brain glutathione deficiency, oxidative stress, glucose uptake, mitochondrial dysfunction." J Gerontol A Biol Sci Med Sci

The Croatian Phase I and II trials reported no serious adverse events

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Kopalli SR, Annamneedi VP, Koppula S (2022) Potential natural biomolecules targeting JAK/STAT/SOCS signaling in the management of atopic dermatitis

A quick glance at the Certificate of Analysis (COA) on this product page (to the side of the product image) details the high levels of purity
