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Role of Peroxiredoxin (PRDX) PRDX is a family of ubiquitously expressed proteins that catalyzes reduction of H 2 O 2 , organic hydroperoxides and peroxynitrite [106]

At birth, males homozygous for 5-reductase-2 mutation typically have a clitoral-like phallus, bifid scrotum, hypospadias, blind shallow vaginal pouch from incomplete closure of the urogenital sinus and a rudimentary prostate (Figure 2 and Figure 3)

Polarized lighting images were performed on a fluorescence microscope (Olympus BX43, Tokyo, Japan) fitted with an analyzer (U-ANT, Olympus) and polarized (U-POT, Olympus)

In vivo experiments indicate that DSF significantly improved the response to anti-PD-1 antibodies (Ab) in a 4T1 breast cancer mouse model, suggesting that the combination of DSF and anti-PD-1 antibodies can activate the tumor immune microenvironment, exhibiting far superior antitumor efficacy compared to monotherapy (155)

Kottayam's relative humidity stays between 67% and 87% year-round, which increases sebum production and pore occlusion

10.1016/j.ajpath.2019.06.004 Am J Pathol