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Familial hypercatabolic hypoproteinemia caused by deficiency of the neonatal Fc receptor, FcRn, due to a mutant beta2-microglobulin gene

The Barthel Index was 72.0130.09, and 37.4% had cognitive impairment

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First, although the application of lessons gained from the ATSP-7041 library resulted in significant improvements in a distinct chemical series (the d PMI-d peptides), it is important to highlight that both series are directed towards the same target(s) (Mdm2/X)

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