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doi: 10.1016/s0891-5849(99)00173-2

Thats not the type of rigorous research needed to establish standard medical care

[cited 2025 Sept 19]

THE GUIDELINES AND PROTOCOLS ADVISORY COMMITTEE The principles of the Guidelines and Protocols Advisory Committee are to: encourage appropriate responses to common medical situations recommend actions that are sufficient and efficient, neither excessive nor deficient permit exceptions when justified by clinical circumstances

These observations derive from preclinical and in vitro research and characterize the compounds studied biochemistry rather than any therapeutic effect