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SCFAs serve as signaling molecules, energy supply, and regulators of metabolism (e.g., insulin sensitivity and fat storage), the immune system, and the gut barrier

doi:10.1016/j.rbmo.2014.01.017

Differential Diagnosis See Vomiting Causes in Children See Vomiting in Pregnancy (Morning Sickness) See Vomiting in Cancer See Psychogenic Vomiting See Medication Induced Vomiting Cannabinoid Hyperemesis Syndrome See Cannabinoid Hyperemesis May be a subset of Cyclic Vomiting Syndrome Chronic Nausea Vomiting Syndrome Other rare conditions with similar presentations Acute Intermittent Porphyria (associated neurologic findings) Disorders of Fatty Acid Metabolism Medium-chain-acyl-CoA Dehydrogenase Deficiency Carnitine palmityltransferase deficiency (deficiency of the mitochondrial translocation) VIII

The gastrointestinal effects are the hallmark and they are directly self-regulating

Obesity and type 2 diabetes impair insulin-induced suppression of glycogenolysis as well as gluconeogenesis
